Inflammatory bowel diseases (IBD) are characterized by a chronic and recurrent gastrointestinal condition, including mainly ulcerative colitis (UC) and Crohn’s disease (CD). Cannabis sativa (CS) is widely used for medicinal, recreational, and religious purposes. The most studied compound of CS is tetrahydrocannabinol (THC) and cannabidiol (CBD). Besides many relevant therapeutic roles such as anti-inflammatory and antioxidant properties, there is still much controversy about the consumption of this plant since the misuse can lead to serious health problems (original abstract available at https://www.ncbi.nlm.nih.gov/pubmed/32331305).
Int J Mol Sci. 2020 Apr 22;21(8). pii: E2940. doi: 10.3390/ijms21082940.
Cannabis and Canabidinoids on the Inflammatory Bowel Diseases: Going Beyond Misuse.
Carvalho A, Souza GA, Marqui SV, Guiguer ÉL, Araújo AC, Rubira CJ, Goulart RA, Flato UAP, Bueno PCDS, Buchaim RL, Barbalho SM.