Cannabis use is associated with changes in brain structure and function; its neurotoxic effects are largely attributed to Δ9-tetrahydrocannabidiol (original abstract available at


Epilepsy Behav Rep. 2019 Nov 9;12:100341. doi: 10.1016/j.ebr.2019.100341. eCollection 2019.
A preliminary study of the effects of cannabidiol (CBD) on brain structure in patients with epilepsy.
Sharma AA, Nenert R, Allendorfer JB, Gaston TE, Grayson LP, Hernando K, Szaflarski JP.